Major Epidemics

 
 
c. 430 B.C.
The Plague of Athens razed the residents of Athens for five years. Science has not confirmed the exact cause of the plague. Among the many possibilities, Typhoid Fever and Ebola have been suggested.
 
165-180 A.D.
The Antonine Plague, also known as the Plague of Galen affected Asia Minor, Egypt, Greece, and Italy and thought it may have been Smallpox or Measles.
 
250-271 A.D.
The Plague of Cyprian, an unidentified epidemic in the Middle East, Africa and Europe.
 
541-542 A.D.
The Plague of Justinian was caused by the Bubonic Plague, and thought to have killed half the population of Europe, afflicting the Byzantine Empire and Mediterranean port cities. Regarded as the first recorded incident of the Bubonic Plague.
 
1346-1353
The Black Death - Bubonic Plague ravaged Europe, Africa, and Asia.
 
1545-1548
The Cocoliztli Epidemic has been identified as a form of viral hemorrhagic fever which attached inhabitants of Mexico and Central America.
 
1657
Measles Outbreak in Boston, Massachusetts
 
1665-1666
Great Plague of London was the last major outbreak of the Black Death's last major outbreak in Great Britain.
 
1687
Measles Outbreak in Boston, Massachusetts
 
1690
Yellow Fever Outbreak in New York.
 
1713
Measles Outbreak in Boston, Massachusetts
 
1729
Measles Outbreak in Boston, Massachusetts
 
1732-33
Worldwide Influenza
 
1738
Smallpox Outbreak in South Carolina
 
1739-40
Measles Outbreak in Boston, Massachusetts
 
1747
Measles Outbreak in Connecticut, New York, Pennsylvania and South Carolina.
 
1759
Measles Outbreak in North America (areas inhabited by white settlers)
 
1761
Influenza Outbreak in North America and West Indies
 
1772
Measles Outbreak in North America
 
1775
Unknown Epidemic in North America Unknown Epidemic - New England hit especially hard
 
1775-76
Worldwide Influenza
 
1783
Dover, Delaware Billous Disorder - extremely fatal
 
1788
Measles Outbreak in New York and Philadelphia, Pennsylvania
 
1793
Putrid Fever and Influenza Outbreak in Vermont
 
1793
Influenza Outbreak in Virginia
 
1793
Yellow Fever Epidemic in Philadelphia, Pennsylvania 
 
1793
Unknown Epidemic in Harrisburg, Pennsylvania 
 
   
1852-1860
Third Cholera Pandemic. Considered as the most deadly of the seven cholera pandemics. Originated in India it moved through Asia, Europe, North Africa and North America.
 
1889-1890
The "Asiatic Flu" or "Russian Flu" saw it's first three cases in Bukhara in Central Asia, Athabasca in northwestern Canada, and Greenland.
 
1910-1911
Sixth Cholera Pandemic originated in India and spread to the Middle East, North Africa, Eastern Europe and Russia. Last outbreak of Cholera in America.
 
1918
Influenza Pandemic spread around the world infecting over one-third of the world's population.
 
1956-1958
Asian Flu Pandemic originated in China and spread to Hong Kong, and the United States. 
 
1968
Flu Pandemic also known as the "Hong Kong Flu" spread from Hong Kong to Vietnam, The Philippines, India, Australia, Europe and the United States.
 
2005-2012
HIV/AIDS Pandemic was first identified in the Democratic Republic of the Congo in 1976 and has affected individuals around the world.
 
   
 
 
 
Websites consulted:
LIVESCIENCE
MPHonline, OUTBREAK: 10 of the Worst Pandemics in History,